Adenomatous polyposis coli in cancer and therapeutic implications

Inactivating mutations of the adenomatous polyposis coli (APC) gene and consequential upregulation of the Wnt signaling pathway are critical initiators in the development of colorectal cancer (CRC), the third most common cancer in the United States for both men and women. Emerging evidence suggests...

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Bibliographic Details
Main Authors: Olivia Noe, Louis Filipiak, Rachel Royfman, Austin Campbell, Leslie Lin, Danae Hamouda, Laura Stanbery, John Nemunaitis
Format: Article
Language:English
Published: PAGEPress Publications 2021-06-01
Series:Oncology Reviews
Subjects:
Online Access:https://oncologyreviews.org/site/article/view/534