Local Delivery of Taxol From FGL-Functionalized Self-Assembling Peptide Nanofiber Scaffold Promotes Recovery After Spinal Cord Injury

Local Delivery of Taxol From FGL-Functionalized Self-Assembling Peptide Nanofiber Scaffold Promotes Recovery After Spinal Cord Injury

Taxol has been clinically approved as an antitumor drug, and it exerts its antitumor effect through the excessive stabilization of microtubules in cancer cells. Recently, moderate microtubule stabilization by Taxol has been shown to efficiently promote neurite regeneration and functional recovery af...

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Bibliographic Details
Main Authors: Zhiyong Xiao, Yingtao Yao, Zhiyu Wang, Qing Tian, Jiedong Wang, Li Gu, Bo Li, Qixin Zheng, Yongchao Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Taxol
spinal cord injury
neurite regeneration
self-assembling peptides
FGL
drug release
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00820/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00820/full

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