Effect of Alpha-Hederin, the active constituent of Nigella sativa, on miRNA-126, IL-13 mRNA levels and inflammation of lungs in ovalbumin-sensitized male rats

Effect of Alpha-Hederin, the active constituent of Nigella sativa, on miRNA-126, IL-13 mRNA levels and inflammation of lungs in ovalbumin-sensitized male rats

Objectives: In previous studies the therapeutic effects of Nigella sativa have been demonstrated on asthmatic animals. In the present study, the preventive effect of single dose of alpha-hederin, its active constituent, has been evaluated on lung inflammation and some inflammatory mediators in lungs...

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Bibliographic Details
Main Authors: Maryam Fallahi, Rana Keyhanmanesh, Amir Mahdi Khamaneh, Mohammad Ali Ebrahimi Saadatlou, Saeideh Saadat, Hadi Ebrahimi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-01-01
Series:Avicenna Journal of Phytomedicine
Subjects:
Alpha-hederin
MiRNA-126
IL-13 mRNA
Ovalbumin
Thymoquinone
Asthma
Online Access:http://ajp.mums.ac.ir/pdf_4622_eb1e17b7fc41beaaceda6589f909135c.html

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http://ajp.mums.ac.ir/pdf_4622_eb1e17b7fc41beaaceda6589f909135c.html

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