Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations.

Standard infectious disease practice calls for aggressive drug treatment that rapidly eliminates the pathogen population before resistance can emerge. When resistance is absent, this elimination strategy can lead to complete cure. However, when resistance is already present, removing drug-sensitive...

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Bibliographic Details
Main Authors: Elsa Hansen, Jason Karslake, Robert J Woods, Andrew F Read, Kevin B Wood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000713