The peroxisome proliferator-activated receptor gamma (PPARγ) agonist, rosiglitazone, ameliorates neurofunctional and neuroinflammatory abnormalities in a rat model of Gulf War Illness.

The peroxisome proliferator-activated receptor gamma (PPARγ) agonist, rosiglitazone, ameliorates neurofunctional and neuroinflammatory abnormalities in a rat model of Gulf War Illness.

<h4>Background</h4>Gulf War (GW) Illness (GWI) is a debilitating condition with a complex constellation of immune, endocrine and neurological symptoms, including cognitive impairment, anxiety and depression. We studied a novel model of GWI based on 3 known common GW exposures (GWE): (i)...

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Bibliographic Details
Main Authors: Kaspar Keledjian, Orest Tsymbalyuk, Stephen Semick, Mitchell Moyer, Serban Negoita, Kevin Kim, Svetlana Ivanova, Volodymyr Gerzanich, J Marc Simard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242427

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https://doi.org/10.1371/journal.pone.0242427

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