Transcriptional activation of ENPP1 by osterix in osteoblasts and osteocytes

Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) is the main source of extracellular pyrophosphate. Along with tissue-nonspecific alkaline phosphatase (TNAP), ENPP1 plays an important role in balancing bone mineralisation. Although well established in pre-osteoblasts, the regulating mechan...

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Bibliographic Details
Main Authors: MM Gao, QN Su, TZ Liang, JX Ma, MJ Stoddart, RG Richards, ZY Zhou, XN Zou
Format: Article
Language:English
Published: AO Research Institute Davos 2018-07-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/papers/vol036/pdf/v036a01.pdf