Visualizing Synaptic Multi-Protein Patterns of Neuronal Tissue With DNA-Assisted Single-Molecule Localization Microscopy

Visualizing Synaptic Multi-Protein Patterns of Neuronal Tissue With DNA-Assisted Single-Molecule Localization Microscopy

The development of super-resolution microscopy (SRM) has widened our understanding of biomolecular structure and function in biological materials. Imaging multiple targets within a single area would elucidate their spatial localization relative to the cell matrix and neighboring biomolecules, reveal...

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Bibliographic Details
Main Authors: Kaarjel K. Narayanasamy, Aleksandar Stojic, Yunqing Li, Steffen Sass, Marina R. Hesse, Nina S. Deussner-Helfmann, Marina S. Dietz, Thomas Kuner, Maja Klevanski, Mike Heilemann
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
single-molecule localization microscopy
super-resolution microscopy
DNA-PAINT
neuronal synapse
multiplexing
Exchange PAINT
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2021.671288/full

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https://www.frontiersin.org/articles/10.3389/fnsyn.2021.671288/full

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