Rho Kinase Activity, Connexin 40, and Atrial Fibrillation: Mechanistic Insights from End-Stage Renal Disease on Dialysis Patients

Rho Kinase Activity, Connexin 40, and Atrial Fibrillation: Mechanistic Insights from End-Stage Renal Disease on Dialysis Patients

Evidence on cellular/molecular mechanisms leading to atrial fibrillation (AF) are scanty. Increased expression of Rho kinase (ROCK) and myosin-phosphatase-target subunit-1 (MYPT-1), ROCK activity’s marker, were shown in AF patients, which correlated with connexin 40 (Cx40) expression, memb...

Full description

Bibliographic Details
Main Authors: Lorenzo A. Calò, Verdiana Ravarotto, Giovanni Bertoldi, Elisa Pagnin, Barbara Rossi, Matteo Rigato, Paul A. Davis, Riccardo Proietti
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Journal of Clinical Medicine
Subjects:
atrial fibrillation
rho kinase
connexin
cardiovascular–renal remodeling
renal failure
Online Access:https://www.mdpi.com/2077-0383/9/1/165

Internet

https://www.mdpi.com/2077-0383/9/1/165

Similar Items