Loss of Nlrp3 Does Not Protect Mice from Western Diet-Induced Adipose Tissue Inflammation and Glucose Intolerance.

Loss of Nlrp3 Does Not Protect Mice from Western Diet-Induced Adipose Tissue Inflammation and Glucose Intolerance.

We tested the hypothesis that loss of Nlrp3 would protect mice from Western diet-induced adipose tissue (AT) inflammation and associated glucose intolerance and cardiovascular complications. Five-week old C57BL6J wild-type (WT) and Nlrp3 knockout (Nlrp3-/-) mice were randomized to either a control d...

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Bibliographic Details
Main Authors: Rebecca E Ringling, Michelle L Gastecki, Makenzie L Woodford, Kelly J Lum-Naihe, Ryan W Grant, Lakshmi Pulakat, Victoria J Vieira-Potter, Jaume Padilla
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5008778?pdf=render

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http://europepmc.org/articles/PMC5008778?pdf=render

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