Loss of Nlrp3 Does Not Protect Mice from Western Diet-Induced Adipose Tissue Inflammation and Glucose Intolerance.
We tested the hypothesis that loss of Nlrp3 would protect mice from Western diet-induced adipose tissue (AT) inflammation and associated glucose intolerance and cardiovascular complications. Five-week old C57BL6J wild-type (WT) and Nlrp3 knockout (Nlrp3-/-) mice were randomized to either a control d...
Main Authors: | Rebecca E Ringling, Michelle L Gastecki, Makenzie L Woodford, Kelly J Lum-Naihe, Ryan W Grant, Lakshmi Pulakat, Victoria J Vieira-Potter, Jaume Padilla |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5008778?pdf=render |
Similar Items
-
The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance
by: Jérémie Gautheron, et al.
Published: (2016-06-01) -
A novel nitroalkene vitamin E analogue inhibits the NLRP3 inflammasome and protects against inflammation and glucose intolerance triggered by obesity
by: Rosina Dapueto, et al.
Published: (2021-02-01) -
Metformin Mitigates Fibrosis and Glucose Intolerance Induced by Doxorubicin in Subcutaneous Adipose Tissue
by: Luana A. Biondo, et al.
Published: (2018-05-01) -
T-lymphocyte responses to intestinally absorbed antigens can contribute to adipose tissue inflammation and glucose intolerance during high fat feeding.
by: Yuehui Wang, et al.
Published: (2010-11-01) -
Host–microbiota interaction induces bi-phasic inflammation and glucose intolerance in mice
by: Antonio Molinaro, et al.
Published: (2017-11-01)