Every Night and Every Morn: Effect of Variation in CLOCK Gene on Depression Depends on Exposure to Early and Recent Stress

Every Night and Every Morn: Effect of Variation in CLOCK Gene on Depression Depends on Exposure to Early and Recent Stress

The role of circadian dysregulation is increasingly acknowledged in the background of depressive symptoms, and is also a promising treatment target. Similarly, stress shows a complex relationship with the circadian system. The CLOCK gene, encoding a key element in circadian regulation has been impli...

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Bibliographic Details
Main Authors: Dorka Gyorik, Nora Eszlari, Zsofia Gal, Dora Torok, Daniel Baksa, Zsuliet Kristof, Sara Sutori, Peter Petschner, Gabriella Juhasz, Gyorgy Bagdy, Xenia Gonda
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Psychiatry
Subjects:
clock gene
depression
stress
childhood adversities
negative life events
gene-environment interactions
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.687487/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2021.687487/full

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