NAP prevents acute cerebral oxidative stress and protects against long-term brain injury and cognitive impairment in a model of neonatal hypoxia–ischemia

NAP prevents acute cerebral oxidative stress and protects against long-term brain injury and cognitive impairment in a model of neonatal hypoxia–ischemia

Hypoxia–ischemia (HI) is a common cause of neonatal brain damage with lifelong morbidities in which current therapies are limited. In this study, we investigated the effect of neuropeptide NAP (NAPVSIPQ) on early cerebral oxidative stress, long-term neurological function and brain injury after neona...

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Bibliographic Details
Main Authors: Samuel Greggio, Simone de Paula, Iuri M. de Oliveira, Cristiano Trindade, Renato M. Rosa, João A.P. Henriques, Jaderson C. DaCosta
Format: Article
Language:English
Published: Elsevier 2011-10-01
Series:Neurobiology of Disease
Subjects:
Perinatal hypoxia–ischemia
NAP
Neuroprotection
Rat model
Oxidative stress
Memory
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111002257

Internet

http://www.sciencedirect.com/science/article/pii/S0969996111002257

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