Neutralization of IL-33 modifies the type 2 and type 3 inflammatory signature of viral induced asthma exacerbation

Abstract Background Respiratory viral infections are one of the leading causes of need for emergency care and hospitalizations in asthmatic individuals, and airway-secreted cytokines are released within hours of viral infection to initiate these exacerbations. IL-33, specifically, contributes to the...

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Bibliographic Details
Main Authors: Kristi J. Warren, Jill A. Poole, Jenea M. Sweeter, Jane M. DeVasure, John D. Dickinson, R. Stokes Peebles, Todd A. Wyatt
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-021-01799-5