Deposition of Doxorubicin in Rats following Administration of Three Newly Synthesized Doxorubicin Conjugates

We previously reported the synthesis of three DOX conjugates that represented different targeting vehicles and showed them to have antitumor activity both in vitro and in vivo. However, the relationships between the pharmacokinetics of these DOX conjugates and their chemical structures were not char...

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Bibliographic Details
Main Authors: Menglei Huan, Shuang Tian, Han Cui, Bangle Zhang, Dan Su, Jieping Wang, Kangchu Li, Weidong Cao
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/926584