Reverse Conservation Analysis Reveals the Specificity Determining Residues of Cytochrome P450 Family 2 (CYP 2)
The concept of conservation of amino acids is widely used to identify important alignment positions of orthologs. The assumption is that important amino acid residues will be conserved in the protein family during the evolutionary process. For paralog alignment, on the other hand, the opposite conce...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2008-01-01
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| Series: | Evolutionary Bioinformatics |
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| Online Access: | http://la-press.com/article.php?article_id=547 |