PCSK7 gene variation bridges atherogenic dyslipidemia with hepatic inflammation in NAFLD patients

PCSK7 gene variation bridges atherogenic dyslipidemia with hepatic inflammation in NAFLD patients

Dyslipidemia and altered iron metabolism are typical features of nonalcoholic fatty liver disease (NAFLD). Proprotein convertase subtilisin/kexin type 7 (PCSK7) gene variation has been associated with circulating lipids and liver damage during iron overload. The aim of this study was to examine the...

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Bibliographic Details
Main Authors: Paola Dongiovanni, Marica Meroni, Guido Baselli, Rosellina M. Mancina, Massimiliano Ruscica, Miriam Longo, Raffaela Rametta, Annalisa Cespiati, Serena Pelusi, Nicola Ferri, Valeria Ranzani, Valerio Nobili, Jussi Pihlajamaki, Anna Ludovica Fracanzani, Sara Badiali, Salvatore Petta, Silvia Fargion, Stefano Romeo, Julia Kozlitina, Luca Valenti
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Journal of Lipid Research
Subjects:
genes in lipid dysfunction
genetics
metabolic disease
nonalcoholic fatty liver disease
proprotein convertase subtilisin/kexin type 7
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520322549

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http://www.sciencedirect.com/science/article/pii/S0022227520322549

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