Regulator of G-Protein Signaling 5 Reduces HeyA8 Ovarian Cancer Cell Proliferation and Extends Survival in a Murine Tumor Model

Regulator of G-Protein Signaling 5 Reduces HeyA8 Ovarian Cancer Cell Proliferation and Extends Survival in a Murine Tumor Model

The regulator of G-protein signaling 5 (RGS5) belongs to a family of GTPase activators that terminate signaling cascades initiated by extracellular mediators and G-protein-coupled receptors. RGS5 has an interesting dual biological role. One functional RGS5 role is as a pericyte biomarker influencing...

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Bibliographic Details
Main Authors: Molly K. Altman, Duy T. Nguyen, Santosh B. Patel, Jada M. Fambrough, Aaron M. Beedle, William J. Hardman, Mandi M. Murph
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Biochemistry Research International
Online Access:http://dx.doi.org/10.1155/2012/518437

Internet

http://dx.doi.org/10.1155/2012/518437

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