Lessons from Drosophila: Engineering Genetic Sexing Strains with Temperature-Sensitive Lethality for Sterile Insect Technique Applications

Lessons from Drosophila: Engineering Genetic Sexing Strains with Temperature-Sensitive Lethality for Sterile Insect Technique Applications

A major obstacle of sterile insect technique (SIT) programs is the availability of robust sex-separation systems for conditional removal of females. Sterilized male-only releases improve SIT efficiency and cost-effectiveness for agricultural pests, whereas it is critical to remove female disease-vec...

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Bibliographic Details
Main Authors: Thu N. M. Nguyen, Amanda Choo, Simon W. Baxter
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Insects
Subjects:
<i>Drosophila melanogaster</i>
embryo lethality
temperature sensitivity
paralysis
CRISPR/Cas9 mutagenesis
Online Access:https://www.mdpi.com/2075-4450/12/3/243

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https://www.mdpi.com/2075-4450/12/3/243

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