Identifying Potential Plasmodium vivax Sporozoite Stage Vaccine Candidates: An Analysis of Genetic Diversity and Natural Selection

Parasite antigen genetic diversity represents a great obstacle when designing a vaccine against malaria caused by Plasmodium vivax. Selecting vaccine candidate antigens has been focused on those fulfilling a role in invasion and which are conserved, thus avoiding specific-allele immune responses. Mo...

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Bibliographic Details
Main Authors: Diego Garzón-Ospina, Sindy P. Buitrago, Andrea E. Ramos, Manuel A. Patarroyo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2018.00010/full