The role of amyloid beta clearance in cerebral amyloid angiopathy: more potential therapeutic targets

Abstract Cerebral amyloid angiopathy (CAA) is characterized by the deposition of amyloid β-protein (Aβ) in the leptomeningeal and cortical blood vessels, which is an age-dependent risk factor for intracerebral hemorrhage (ICH), ischemic stroke and contributes to cerebrovascular dysfunction leading t...

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Bibliographic Details
Main Authors: Xue-mei Qi, Jian-fang Ma
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Translational Neurodegeneration
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40035-017-0091-7