Asymmetric Regulation of Peripheral Genes by Two Transcriptional Regulatory Networks.

Transcriptional regulatory network (TRN) reconstitution and deconstruction occur simultaneously during reprogramming; however, it remains unclear how the starting and targeting TRNs regulate the induction and suppression of peripheral genes. Here we analyzed the regulation using direct cell reprogra...

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Bibliographic Details
Main Authors: Jing-Ru Li, Takahiro Suzuki, Hajime Nishimura, Mami Kishima, Shiori Maeda, Harukazu Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4970704?pdf=render