Targeting a cysteine protease from a pathobiont alleviates experimental arthritis
Abstract Background Several lines of evidence suggest that the pathobiont Porphyromonas gingivalis is involved in the development and/or progression of auto-inflammatory diseases. This bacterium produces cysteine proteases, such as gingipain RgpA, endowed with the potential to induce significant bon...
Main Authors: | Hsin-Yi Peng, Shih-Yao Chen, Shih-Hong Siao, Jinghua Tsai Chang, Ting-Yin Xue, Yi-Hsuan Lee, Ming-Shiou Jan, Gregory J. Tsay, Moncef Zouali |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
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Series: | Arthritis Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13075-020-02205-z |
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