Nocturnal hypercapnia with daytime normocapnia in patients with advanced pulmonary arterial hypertension awaiting lung transplantation.

BACKGROUND:Pulmonary arterial hypertension (PAH) is frequently complicated by sleep disordered breathing (SDB), and previous studies have largely focused on hypoxemic SDB. Even though nocturnal hypercapnia was shown to exacerbate pulmonary hypertension, the clinical significance of nocturnal hyperca...

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Main Authors: Yoshinari Nakatsuka, Toyofumi Chen-Yoshikawa, Hideyuki Kinoshita, Akihiro Aoyama, Hiroyasu Kubo, Kimihiko Murase, Satoshi Hamada, Hirofumi Takeyama, Takuma Minami, Naomi Takahashi, Kiminobu Tanizawa, Tomohiro Handa, Toyohiro Hirai, Hiroshi Date, Kazuo Chin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0227775