The intermediate filament network in cultured human keratinocytes is remarkably extensible and resilient.

The prevailing model of the mechanical function of intermediate filaments in cells assumes that these 10 nm diameter filaments make up networks that behave as entropic gels, with individual intermediate filaments never experiencing direct loading in tension. However, recent work has shown that singl...

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Bibliographic Details
Main Authors: Douglas Fudge, David Russell, Dan Beriault, Whitney Moore, E Birgitte Lane, A Wayne Vogl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2390850?pdf=render