Prostaglandin E2 reduces the release and infectivity of new cell-free virions and cell-to-cell HIV-1 transfer.

<h4>Background</h4>The course of human immunodeficiency virus type-1 (HIV-1) infection is influenced by a complex interplay between viral and host factors. HIV infection stimulates several proinflammatory genes, such as cyclooxigense-2 (COX-2), which leads to an increase in prostaglandin...

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Bibliographic Details
Main Authors: María Isabel Clemente, Susana Álvarez, María Jesús Serramía, Marta Martínez-Bonet, María Ángeles Muñoz-Fernández
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24586238/pdf/?tool=EBI