SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism.

SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism.

Severe acute respiratory syndrome coronavirus (SARS-CoV) infection often caused severe end stage lung disease and organizing phase diffuse alveolar damage, especially in the elderly. The virus-host interactions that governed development of these acute end stage lung diseases and death are unknown. T...

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Bibliographic Details
Main Authors: Matthew B Frieman, Jun Chen, Thomas E Morrison, Alan Whitmore, William Funkhouser, Jerrold M Ward, Elaine W Lamirande, Anjeanette Roberts, Mark Heise, Kanta Subbarao, Ralph S Baric
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20386712/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20386712/pdf/?tool=EBI

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