Genetic Variants in Patients with Multiple Head and Neck Paragangliomas: Dilemma in Management

Genetic Variants in Patients with Multiple Head and Neck Paragangliomas: Dilemma in Management

Multiple head and neck paragangliomas (HNPGLs) are neuroendocrine tumors of a mostly benign nature that can be associated with a syndrome, precipitated by the presence of a germline mutation. Familial forms of the disease are usually seen with mutations of <i>SDHx</i> genes, especially t...

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Bibliographic Details
Main Authors: Anasuya Guha, Ales Vicha, Tomas Zelinka, Zdenek Musil, Martin Chovanec
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomedicines
Subjects:
HNPGL
<i>SDHD</i> gene
<i>SDHB</i> gene
germline mutation
carotid body tumors
malignant paragangliomas
Online Access:https://www.mdpi.com/2227-9059/9/6/626

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https://www.mdpi.com/2227-9059/9/6/626

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