The microbiome composition of Aedes aegypti is not critical for Wolbachia-mediated inhibition of dengue virus.

BACKGROUND:Dengue virus (DENV) is primarily vectored by the mosquito Aedes aegypti, and is estimated to cause 390 million human infections annually. A novel method for DENV control involves stable transinfection of Ae. aegypti with the common insect endosymbiont Wolbachia, which mediates an antivira...

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Bibliographic Details
Main Authors: Michelle D Audsley, Yixin H Ye, Elizabeth A McGraw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5357062?pdf=render