IMCA Induces Ferroptosis Mediated by SLC7A11 through the AMPK/mTOR Pathway in Colorectal Cancer

Ferroptosis, implicated in several diseases, is a new form of programmed and nonapoptotic cell death triggered by iron-dependent lipid peroxidation after inactivation of the cystine/glutamate antiporter system xc–, which is composed of solute carrier family 7 membrane 11 (SLC7A11) and solute carrier...

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Bibliographic Details
Main Authors: Lei Zhang, Wen Liu, Fangyan Liu, Qun Wang, Mengjiao Song, Qi Yu, Kun Tang, Tieshan Teng, Dongdong Wu, Xijing Wang, Wuqi Han, Yanzhang Li
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/1675613