Regulation of epidermal sphingolipid synthesis by permeability barrier function.

A mixture of sphingolipids, cholesterol, and free fatty acids forms the intercellular membrane bilayers of the stratum corneum which are presumed to regulate epidermal barrier function. Prior studies have shown that both cholesterol and fatty acid synthesis are rapidly regulated by epidermal barrier...

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Bibliographic Details
Main Authors: WM Holleran, KR Feingold, MQ Man, WN Gao, JM Lee, PM Elias
Format: Article
Language:English
Published: Elsevier 1991-07-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520419789