Development and evaluation of mucoadhesive bigel containing tenofovir and maraviroc for HIV prophylaxis

Abstract Background Sexual transmission of HIV is the most common means of acquiring the disease. Topical microbicides have been investigated to prevent transmission. This study will use a specific entry inhibitor, maraviroc, and a nucleotide reverse transcriptase inhibitor (NRTI), tenofovir, a dual...

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Bibliographic Details
Main Authors: Margaret O. Ilomuanya, Ayotunde T. Hameedat, Edidiong N Akang, Sabdat O. Ekama, Boladale O. Silva, Alani S Akanmu
Format: Article
Language:English
Published: SpringerOpen 2020-11-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
HIV
Online Access:http://link.springer.com/article/10.1186/s43094-020-00093-3