New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection

New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection

3-Iodothyronamine (T1AM) is an endogenous high-affinity ligand of the trace amine-associated receptor 1 (TAAR1), detected in mammals in many organs, including the brain. Recent evidence indicates that pharmacological TAAR1 activation may offer a novel therapeutic option for the treatment of a wide r...

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Bibliographic Details
Main Authors: Lorenza Bellusci, Annunziatina Laurino, Martina Sabatini, Simona Sestito, Paola Lenzi, Laura Raimondi, Simona Rapposelli, Francesca Biagioni, Francesco Fornai, Alessandra Salvetti, Leonardo Rossi, Riccardo Zucchi, Grazia Chiellini
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Pharmacology
Subjects:
thyronamines
trace amine-associated receptors
learning
memory
neuroprotection
autophagy
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00905/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00905/full

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