The integration of HR-HPV increases the expression of cyclins A and E in cytologies with and without low-grade lesions

The integration of HR-HPV increases the expression of cyclins A and E in cytologies with and without low-grade lesions

Background: Cyclin-A and cyclin-E are regulators of G1-S phase of normal cell cycle. Integration of human papilloma virus high-risk (HR-HPV) could alter this mechanism, and its overexpression has been associated with poor prognosis in cervical cancer. Aim: To determine the expression of cyclin-A and...

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Bibliographic Details
Main Authors: M I Zubillaga-Guerrero, B Illades-Aguiar, M A Leyva-Vazquez, E Flores-Alfaro, E Castañeda-Saucedo, J F Muñoz-Valle, L C Alarcón-Romero
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Journal of Cytology
Subjects:
Cyclin-A; cyclin-E; high-risk human papillomavirus; in situ hybridization; low-grade squamous intraepithelial lesion
Online Access:http://www.jcytol.org/article.asp?issn=0970-9371;year=2013;volume=30;issue=1;spage=1;epage=7;aulast=Zubillaga-Guerrero

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http://www.jcytol.org/article.asp?issn=0970-9371;year=2013;volume=30;issue=1;spage=1;epage=7;aulast=Zubillaga-Guerrero

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