The integration of HR-HPV increases the expression of cyclins A and E in cytologies with and without low-grade lesions
Background: Cyclin-A and cyclin-E are regulators of G1-S phase of normal cell cycle. Integration of human papilloma virus high-risk (HR-HPV) could alter this mechanism, and its overexpression has been associated with poor prognosis in cervical cancer. Aim: To determine the expression of cyclin-A and...
Main Authors: | M I Zubillaga-Guerrero, B Illades-Aguiar, M A Leyva-Vazquez, E Flores-Alfaro, E Castañeda-Saucedo, J F Muñoz-Valle, L C Alarcón-Romero |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2013-01-01
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Series: | Journal of Cytology |
Subjects: | |
Online Access: | http://www.jcytol.org/article.asp?issn=0970-9371;year=2013;volume=30;issue=1;spage=1;epage=7;aulast=Zubillaga-Guerrero |
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