Inflammatory Microenvironment and Specific T Cells in Myeloproliferative Neoplasms: Immunopathogenesis and Novel Immunotherapies

Inflammatory Microenvironment and Specific T Cells in Myeloproliferative Neoplasms: Immunopathogenesis and Novel Immunotherapies

The Philadelphia-negative myeloproliferative neoplasms (MPNs) are malignancies of the hematopoietic stem cell (HSC) arising as a consequence of clonal proliferation driven by somatically acquired driver mutations in discrete genes (JAK2, CALR, MPL). In recent years, along with the advances in molecu...

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Bibliographic Details
Main Authors: Vincenzo Nasillo, Giovanni Riva, Ambra Paolini, Fabio Forghieri, Luca Roncati, Beatrice Lusenti, Monica Maccaferri, Andrea Messerotti, Valeria Pioli, Andrea Gilioli, Francesca Bettelli, Davide Giusti, Patrizia Barozzi, Ivana Lagreca, Rossana Maffei, Roberto Marasca, Leonardo Potenza, Patrizia Comoli, Rossella Manfredini, Antonino Maiorana, Enrico Tagliafico, Mario Luppi, Tommaso Trenti
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
MPN
inflammation
immunity
T cells
niche
PV
Online Access:https://www.mdpi.com/1422-0067/22/4/1906

Internet

https://www.mdpi.com/1422-0067/22/4/1906

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