Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses

Several viruses in the Arenaviridae family infect humans and cause severe hemorrhagic fevers which lead to high case fatality rates. Due to their pathogenicity and geographic tropisms, these viruses remain very understudied. As a result, an effective vaccine or therapy is urgently needed. Here, we d...

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Bibliographic Details
Main Authors: Fatima Amanat, James Duehr, Lisa Oestereich, Kathryn M. Hastie, Erica Ollmann Saphire, Florian Krammer
Format: Article
Language:English
Published: American Society for Microbiology 2018-05-01
Series:mSphere
Subjects:
GP2
GPC
Online Access:https://doi.org/10.1128/mSphere.00189-18