Internal radiation dosimetry of a 152Tb-labeled antibody in tumor-bearing mice

Internal radiation dosimetry of a 152Tb-labeled antibody in tumor-bearing mice

Abstract Background Biodistribution studies based on organ harvesting represent the gold standard pre-clinical technique for dose extrapolations. However, sequential imaging is becoming increasingly popular as it allows the extraction of longitudinal data from single animals, and a direct correlatio...

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Bibliographic Details
Main Authors: Francesco Cicone, Silvano Gnesin, Thibaut Denoël, Thierry Stora, Nicholas P. van der Meulen, Cristina Müller, Christiaan Vermeulen, Martina Benešová, Ulli Köster, Karl Johnston, Ernesto Amato, Lucrezia Auditore, George Coukos, Michael Stabin, Niklaus Schaefer, David Viertl, John O. Prior
Format: Article
Language:English
Published: SpringerOpen 2019-06-01
Series:EJNMMI Research
Subjects:
microPET
Small animal dosimetry
152Tb
OLINDA/EXM® 2.0
Biodistribution
Organ harvesting
Online Access:http://link.springer.com/article/10.1186/s13550-019-0524-7

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http://link.springer.com/article/10.1186/s13550-019-0524-7

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