Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance

Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance

Insulin resistance is a chronic inflammatory condition accompanying obesity or high fat diets that leads to type 2 diabetes. It is hypothesized that lipids and gut bacterial compounds in particular contribute to metabolic inflammation by activating the immune system; however, the receptors detecting...

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Bibliographic Details
Main Authors: Kenny L. Chan, Theresa H. Tam, Parastoo Boroumand, David Prescott, Sheila R. Costford, Nichole K. Escalante, Noah Fine, YuShan Tu, Susan J. Robertson, Dilshaayee Prabaharan, Zhi Liu, Philip J. Bilan, Michael W. Salter, Michael Glogauer, Stephen E. Girardin, Dana J. Philpott, Amira Klip
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Cell Reports
Subjects:
inflammation
insulin resistance
gut microbiome
macrophage
neutrophil
NOD1
obesity
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717302085

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http://www.sciencedirect.com/science/article/pii/S2211124717302085

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