The Role of the Receptor Tyrosine Kinase Axl in Carcinogenesis and Development of Therapeutic Resistance: An Overview of Molecular Mechanisms and Future Applications

Resistance to chemotherapeutic agents by cancer cells has remained a major obstacle in the successful treatment of various cancers. Numerous factors such as DNA damage repair, cell death inhibition, epithelial–mesenchymal transition, and evasion of apoptosis have all been implicated in the promotion...

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Bibliographic Details
Main Authors: Martha Wium, Aderonke F. Ajayi-Smith, Juliano D. Paccez, Luiz F. Zerbini
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
Axl
Online Access:https://www.mdpi.com/2072-6694/13/7/1521