Baseline immune profile by CyTOF can predict response to an investigational adjuvanted vaccine in elderly adults

Abstract Background Mass cytometry, or CyTOF (Cytometry by Time-of-Flight), permits the simultaneous detection of over 40 phenotypic and functional immune markers in individual cells without the issues of spectral overlap seen in traditional flow cytometry. Methods In this study, we applied CyTOF to...

Full description

Bibliographic Details
Main Authors: Christine M. D. Lingblom, Sangeeta Kowli, Nithya Swaminathan, Holden T. Maecker, Stacie L. Lambert
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Translational Medicine
Subjects:
RSV
Online Access:http://link.springer.com/article/10.1186/s12967-018-1528-1