Are Anticholinergic Symptoms a Risk Factor for Falls in Older General Practice Patients With Polypharmacy? Study Protocol for the Development and Validation of a Prognostic Model

Are Anticholinergic Symptoms a Risk Factor for Falls in Older General Practice Patients With Polypharmacy? Study Protocol for the Development and Validation of a Prognostic Model

Background: Cumulative anticholinergic exposure, also known as anticholinergic burden, is associated with a variety of adverse outcomes. However, studies show that anticholinergic effects tend to be underestimated by prescribers, and anticholinergics are the most frequently prescribed potentially in...

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Bibliographic Details
Main Authors: Truc Sophia Dinh, Ana Isabel González-González, Andreas D. Meid, Kym I. E. Snell, Henrik Rudolf, Maria-Sophie Brueckle, Jeanet W. Blom, Ulrich Thiem, Hans-Joachim Trampisch, Petra J. M. Elders, Norbert Donner-Banzhoff, Ferdinand M. Gerlach, Sebastian Harder, Marjan van den Akker, Paul P. Glasziou, Walter E. Haefeli, Christiane Muth
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
aged [MesH]
anticholinergic burden
accidental falls [MeSH]
general practice
prediction model
prognosis research
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.577747/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.577747/full

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