Evaluation of reaction gap-filling accuracy by randomization

Evaluation of reaction gap-filling accuracy by randomization

Abstract Background Completion of genome-scale flux-balance models using computational reaction gap-filling is a widely used approach, but its accuracy is not well known. Results We report on computational experiments of reaction gap filling in which we generated degraded versions of the EcoCyc-20.0...

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Bibliographic Details
Main Authors: Mario Latendresse, Peter D. Karp
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Bioinformatics
Subjects:
Flux balance analysis
FBA
Gap-filling
Evaluation
Randomization
Online Access:http://link.springer.com/article/10.1186/s12859-018-2050-4

Internet

http://link.springer.com/article/10.1186/s12859-018-2050-4

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