Filament-filament switching can be regulated by separation between filaments together with cargo motor number.

How intracellular transport controls the probability that cargos switch at intersections between filaments is not well understood. In one hypothesis some motors on the cargo attach to one filament while others attach to the intersecting filament, and the ensuing tug-of-war determines which filament...

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Bibliographic Details
Main Authors: Robert P Erickson, Steven P Gross, Clare C Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3573032?pdf=render