Chemically Induced Oncogenesis in the Peripheral Nervous System Is Suppressed in Congenic BDIX.BDIV-Mss1 and -Mss7 Rats

Chemically Induced Oncogenesis in the Peripheral Nervous System Is Suppressed in Congenic BDIX.BDIV-Mss1 and -Mss7 Rats

Human malignant peripheral nerve sheath tumors (MPNSTs) are highly aggressive soft-tissue sarcomas with a poor prognosis that arise either in the context of neurofibromatosis 1 or sporadically. Inbred BDIX and BDIV rat strains highly susceptible and resistant, respectively, to the development of eth...

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Bibliographic Details
Main Authors: Bernd Koelsch, Linda van den Berg, Christine Fischer, Bettina Winzen-Reichert, Andrea Kutritz, Andrea Kindler-Röhrborn
Format: Article
Language:English
Published: Oxford University Press 2016-01-01
Series:G3: Genes, Genomes, Genetics
Subjects:
cancer risk
malignant schwannoma
rodent
sex difference
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.115.021170

Internet

http://g3journal.org/lookup/doi/10.1534/g3.115.021170

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