Exosomes secreted by adipose-derived mesenchymal stem cells regulate type I collagen metabolism in fibroblasts from women with stress urinary incontinence

Abstract Background Mesenchymal stem cells (MSC) have gained credibility as a therapeutic tool partly due to their potential to secrete factors such as cytokines and chemokines. Recently, exosomes, which mediate intercellular communication by delivering biomolecules such as mRNA and miRNA into recip...

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Bibliographic Details
Main Authors: Xiaochun Liu, Shiwei Wang, Suhui Wu, Qian Hao, Ying Li, Zhuodan Guo, Wenzhen Wang
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-018-0899-9