Influence of the serotonin transporter 5HTTLPR polymorphism on symptom severity in irritable bowel syndrome.

5HTTLPR polymorphism of serotonin transporter yields short (S) and long (L) alleles. SS and LS genotypes are associated with reduced expression of serotonin transporter. This cross-sectional study investigated the association of 5HTTLPR with symptom severity of irritable bowel syndrome (IBS). Patien...

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Main Authors: Rocchina Colucci, Dario Gambaccini, Narcisa Ghisu, Giuseppe Rossi, Francesco Costa, Marco Tuccori, Nicola De Bortoli, Matteo Fornai, Luca Antonioli, Angelo Ricchiuti, Maria Gloria Mumolo, Santino Marchi, Corrado Blandizzi, Massimo Bellini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3564922?pdf=render