Lysophosphatidylcholine as an effector of fatty acid-induced insulin resistance[S]

The mechanism of FFA-induced insulin resistance is not fully understood. We have searched for effector molecules(s) in FFA-induced insulin resistance. Palmitic acid (PA) but not oleic acid (OA) induced insulin resistance in L6 myotubes through C-Jun N-terminal kinase (JNK) and insulin receptor subst...

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Main Authors: Myoung Sook Han, Yu-Mi Lim, Wenying Quan, Jung Ran Kim, Kun Wook Chung, Mira Kang, Sunshin Kim, Sun Young Park, Joong-Soo Han, Shin-Young Park, Hyae Gyeong Cheon, Sang Dal Rhee, Tae-Sik Park, Myung-Shik Lee
Format: Article
Language:English
Published: Elsevier 2011-06-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520313419