Uric acid induced hepatocytes lipid accumulation through regulation of miR-149-5p/FGF21 axis

Abstract Background Hyperuricemia is a major risk for non-alcoholic fatty liver disease. However, the mechanisms for this phenomenon are not fully understood. This study aimed to investigate whether microRNAs mediated the pathogenic effects of uric acid on non-alcoholic fatty liver disease. Methods...

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Bibliographic Details
Main Authors: Shenghui Chen, Dan Chen, Hua Yang, Xinyu Wang, Jinghua Wang, Chengfu Xu
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Gastroenterology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12876-020-01189-z