The "Phantom Effect" of the Rexinoid LG100754: structural and functional insights.

The "Phantom Effect" of the Rexinoid LG100754: structural and functional insights.

Retinoic acid receptors (RARs) and Retinoid X nuclear receptors (RXRs) are ligand-dependent transcriptional modulators that execute their biological action through the generation of functional heterodimers. RXR acts as an obligate dimer partner in many signalling pathways, gene regulation by rexinoi...

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Bibliographic Details
Main Authors: Yoshiteru Sato, Nick Ramalanjaona, Tiphaine Huet, Noelle Potier, Judit Osz, Pierre Antony, Carole Peluso-Iltis, Pierre Poussin-Courmontagne, Eric Ennifar, Yves Mély, Annick Dejaegere, Dino Moras, Natacha Rochel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2994906?pdf=render

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http://europepmc.org/articles/PMC2994906?pdf=render

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