Early brain connectivity alterations and cognitive impairment in a rat model of Alzheimer’s disease
Abstract Background Animal models of Alzheimer’s disease (AD) are essential to understanding the disease progression and to development of early biomarkers. Because AD has been described as a disconnection syndrome, magnetic resonance imaging (MRI)-based connectomics provides a highly translational...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-02-01
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Series: | Alzheimer’s Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13195-018-0346-2 |