Early brain connectivity alterations and cognitive impairment in a rat model of Alzheimer’s disease

Abstract Background Animal models of Alzheimer’s disease (AD) are essential to understanding the disease progression and to development of early biomarkers. Because AD has been described as a disconnection syndrome, magnetic resonance imaging (MRI)-based connectomics provides a highly translational...

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Bibliographic Details
Main Authors: Emma Muñoz-Moreno, Raúl Tudela, Xavier López-Gil, Guadalupe Soria
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Alzheimer’s Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13195-018-0346-2